“The use of blue light in the treatment of skin lesions”
EmoLED is investigating the effect of blue LED light on skin lesions in collaboration with leading Italian research centers in physics and medicine.
Studies have shown that ulcers of the lower legs (venous, arterial and mixed ulcers), inflammatory ulcers from rheumatic diseases, scleroderma, diabetic foot and pressure ulcers, skin lesions with tissue loss such as fire and trauma wounds, surgical wound openings and dermatosis such as atopic dermatitis. over a wide range of diseases, including
This research revealed that blue light can stimulate skin tissue regeneration through the process of resolving inflammation and photobiomodulation.
“Origins”
While people have been using sunlight to treat certain diseases since ancient times, modern phototherapy emerged as a result of the work of Danish dermatologist Finsen. Finsen was awarded the Nobel Prize in Medicine in 1903 after the publication of the results of treating lupus vulgaris using intense, UV-rich light produced by an arc lamp.
With the development of lasers and later LEDs (Light Emitting Dijodes) in the 60s, light sources that emit "monochromatic" light emerged and it became possible to investigate the interaction between biological tissues and specific wavelengths. This was the birth of the branch of physics called biophotonics, which led to the development of a variety of medical devices for therapeutic and diagnostic treatments.
“Therapeutic mechanism of blue light: Photobiomodulation”
The therapeutic effect of light occurs due to the presence of endogenous molecules that can absorb light. The energy transmitted by the signal spectrum is absorbed by these naturally occurring elements, "chromophores", and is used to induce chemical reactions or produce conformational changes in certain biomolecules.
This process translates into beneficial therapeutic effects such as pain reduction and inflammation reduction. Immunomodulation and stimulation of wound healing and tissue regeneration were defined as “Photobiomodulation” in a joint conference by the North American Laser Therapy Association and the World Laser Therapy Association in 2014.
Each chromophore has a different absorption spectrum and therefore has a variety of wavelengths with different sensitivities that can lead to varying photophysical and photochemical effects when absorbed by tissues.
EmoLED has developed a photobiomodulation-based therapy for skin lesions using specific wavelengths in the blue range. Blue light is absorbed by electron transport chain enzymes and flavoproteins.
